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The biggest of the studies included 135 overweight individuals, which were split into two groups (7): Treatment group: 1 gram of Garcinia Cambogia Extract, 3 times per day, taken 30 minutes before meals. Placebo group: The other group took dummy pills (placebo). Both groups also went on a high-fiber, low calorie diet. These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al.